Prescription Savings Card

Burke's Main Street Pharmacy
Prescription Savings Card

Tired of Paying Too Much for Prescriptions?

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How It Works

Start Saving Today!

The Burke's Main Street Pharmacy pharmacy savings program gives millions of cardholders across the United States and Puerto Rico free access to discounts on prescription medications. Our program can be used by every member of the family including pets and can save you money even if you have prescription benefits.

How does Burke's Main Street Pharmacy do it? Our tremendous volume allows us to negotiate discounts with over 67,000 participating pharmacies nationwide and pass those savings directly on to you. Our online search tool allows you to compare prices at local pharmacies without leaving your home.

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Mission Statement

Our Mission is to Save You Money

Burke's Main Street Pharmacy is dedicated to helping improve the health and wellness of all individuals and their pets by giving them access to affordable prescription medications.

Find out more about us and the organizations we partner with.

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Program Highlights

Too Good NOT to be True

The Burke's Main Street Pharmacy medication savings program provides discounts of up to 87% off retail prices at all major chains and most independent pharmacies nationwide.

  • Absolutely FREE access to savings

    And you will always pay the lower of your insurance copay, the cash price or the Burke's Main Street Pharmacy discounted price.

  • Works on all FDA approved medications

    Including over-the-counter medications with a valid prescription.

  • Never Expires

    You can use the same card again and again at all participating pharmacies unlike single use coupons.

  • No enrollment or personal information required

    Burke's Main Street Pharmacy is always active with no registration to complete, and no setup or subscription fees.

  • Accepted at 67,000+ pharmacies nationwide

    Including all major retail pharmacies, big box stores, supermarkets and most independent pharmacies.

  • Works for Pet Medications

    If your pet has a prescription that has a human equivalent, our program can help.

  • Everyone is eligible

    No income or age restrictions.

  • Works for insured, uninsured and underinsured

    Everyone has the ability to save with our free card.

  • Multiple ways to get your free card

    Either print, text, email, download or request a physical card to be mailed. You can even share it on Facebook and Twitter.

What People Are Saying

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Recent Member Savings

This Could be You!

Use our online pricing tool to find local pharmacies with the lowest price for your medications.

Medication Count Retail Paid Savings Pharmacy Location
AMOXICILLIN 500 MG TABLET 21 $64.29 $11.18 $53.11 83% STANLEY PHARMACY SEARCY, AR
CYCLOBENZAPRINE 10 MG TABLET 60 $83.95 $7.75 $76.20 91% THE APOTHECARY STAFFORD, TX
DICLOFENAC SODIUM 1% GEL 100 $127.50 $20.01 $107.49 84% YORKTOWN PHARMACY ELKINS PARK, PA
IBUPROFEN 800 MG TABLET 84 $72.62 $18.98 $53.64 74% TRUST PHARMACY TAMPA, FL
FOLIC ACID 1 MG TABLET 90 $29.68 $5.83 $23.85 80% EXPRESS RX OF VARDAMAN VARDAMAN, MS
LEVONORGESTREL-ETH ESTRAD 0.15 91 $114.99 $45.94 $69.05 60% CVS/pharmacy PHENIX CITY, AL
METOPROLOL SUCC ER 50 MG TAB 30 $15.59 $1.76 $13.83 89% CVS/pharmacy ROCKYRIVER, OH
METHYLPREDNISOLONE 4 MG DOSEPK 21 $68.50 $15.71 $52.79 77% EXPRESS RX AT OTTER CREEK LITTLE ROCK, AR
TADALAFIL 5 MG TABLET 30 $578.31 $16.20 $562.11 97% EXPRESS RX OF PLEASANT VIEW PLEASANT VIEW, TN
AMLODIPINE BESYLATE 10 MG TAB 30 $76.28 $6.99 $69.29 91% SALUMED PHARMACY BRENTWOOD BRENTWOOD, NY
LOSARTAN POTASSIUM 25 MG TAB 30 $262.80 $11.82 $250.98 96% STANLEY PHARMACY SEARCY, AR
PHENTERMINE 37.5 MG TABLET 30 $39.99 $12.51 $27.48 69% CVS/pharmacy SLIDELL, LA
PREVIDENT 5000 ENAMEL PROTECT 100 $37.99 $21.72 $16.27 43% Walgreens BONITA SPRINGS, FL
ONDANSETRON ODT 4 MG TABLET 18 $2,018.34 $14.69 $2,003.65 99% STANLEY PHARMACY SEARCY, AR
ALPRAZOLAM 0.5 MG TABLET 25 $314.06 $7.55 $306.51 98% WESTERN DRUG SPRINGERVILLE, AZ
METHOTREXATE 2.5 MG TABLET 36 $180.17 $25.31 $154.86 86% CORNERSTONE APOTHECARY VAN HORNE, IA
FREESTYLE LIBRE 14 DAY SENSOR 3 $263.89 $223.41 $40.48 15% Walgreens MIDLAND, GA
MONTELUKAST SOD 10 MG TABLET 30 $257.32 $10.53 $246.79 96% EXPRESS RX OF UNION UNION, MS
TADALAFIL 5 MG TABLET 90 $1,385.12 $25.43 $1,359.69 98% BLUEGRASS DRUG STORE DANVILLE, KY
SILDENAFIL 100 MG TABLET 10 $288.80 $15.96 $272.84 94% Walmart HOUSTON, TX
FLUOXETINE HCL 20 MG CAPSULE 30 $404.21 $8.68 $395.53 98% STANLEY PHARMACY SEARCY, AR
GNP SENNA LAX 8.6 MG TABLET 60 $26.60 $7.48 $19.12 72% EAST HAWAII HEALTH PHARMACY HILO, HI
METHYLPREDNISOLONE 4 MG DOSEPK 21 $39.65 $9.40 $30.25 76% SALUMED PHARMACY BRENTWOOD BRENTWOOD, NY
WIXELA 250-50 INHUB 60 $314.99 $96.07 $218.92 70% CVS/pharmacy BLUFFTON, SC
PREDNISOLONE AC 1% EYE DROP 10 $174.76 $43.78 $130.98 75% EXPRESS RX OF HEBER SPRINGS HEBER SPRINGS, AR
SPIRONOLACTONE 25 MG TABLET 90 $58.14 $12.74 $45.40 78% WILLIAMSBURG DRUG COMPANY INC WILLIAMSBURG, VA
TRAMADOL HCL 50 MG TABLET 56 $65.42 $8.84 $56.58 86% COLORA PHARMACY COLORA, MD
TADALAFIL 5 MG TABLET 30 $578.31 $16.20 $562.11 97% EXPRESS RX OF PINE BLUFF PINE BLUFF, AR
FENOFIBRATE 160 MG TABLET 90 $316.04 $66.19 $249.85 79% BONHAMTOWN PHARMACY EDISON, NJ
SILDENAFIL 20 MG TABLET 20 $492.57 $13.48 $479.09 97% EAST HAWAII HEALTH PHARMACY HILO, HI
ANASTROZOLE 1 MG TABLET 10 $206.84 $31.27 $175.57 85% EXPRESS RX AT NATIONAL PARK HOT SPRINGS, AR
ETONOGESTREL-EE VAGINAL RING 3 $660.49 $88.55 $571.94 87% Harris Teeter APEX, NC
OXYCODONE HCL (IR) 30 MG TAB 96 $349.57 $28.31 $321.26 92% MIX IT RX MISSOURI CITY, TX
VITAMIN D2 1.25 MG(50,000 UNIT 4 $17.88 $6.76 $11.12 62% MEDISAVE PHARMACY CAMDEN, SC
VITAMIN D2 1.25 MG(50,000 UNIT 4 $31.04 $5.81 $25.23 81% EXPRESS RX OF PINE BLUFF PINE BLUFF, AR
LISINOPRIL 20 MG TABLET 30 $35.60 $8.81 $26.79 75% CIRCLE S PHARMACY PAHOKEE, FL
MYRBETRIQ ER 25 MG TABLET 30 $615.60 $507.52 $108.08 18% SYMBRIA RX SERVICES WOODRIDGE, IL
TAMSULOSIN HCL 0.4 MG CAPSULE 90 $327.99 $17.78 $310.21 95% ST JOHNS DRUG ST JOHNS, AZ
PHENTERMINE 37.5 MG TABLET 30 $42.95 $13.06 $29.89 70% Publix LYNN HAVEN, FL
LOSARTAN POTASSIUM 50 MG TAB 90 $208.67 $16.14 $192.53 92% AMERICAS PHARMACY UNION CITY, NJ
SILDENAFIL 20 MG TABLET 90 $1,408.99 $23.75 $1,385.24 98% Rite Aid SHERMANS DALE, PA
ALENDRONATE SODIUM 10 MG TAB 90 $278.99 $31.95 $247.04 89% Rite Aid ALTURAS, CA
CLOTRIMAZOLE-BETAMETHASONE CRM 30 $63.99 $18.06 $45.93 72% CVS/pharmacy CHARLOTTE, NC
MELOXICAM 7.5 MG TABLET 15 $312.84 $6.94 $305.90 98% WESTERN DRUG SPRINGERVILLE, AZ
ROSUVASTATIN CALCIUM 10 MG TAB 30 $140.99 $12.67 $128.32 91% CVS/pharmacy RYE BROOK, NY
OXYCODONE-ACETAMINOPHEN 5-325 15 $21.69 $4.47 $17.22 79% CVS/pharmacy NORTH BERGEN, NJ
CYANOCOBALAMIN 1,000 MCG/ML VL 1 $25.41 $5.81 $19.60 77% EXPRESS RX OF TAYLORSVILLE TAYLORSVILLE, KY
FAMOTIDINE 40 MG TABLET 60 $59.99 $8.19 $51.80 86% Savon FOX LAKE, IL
PANTOPRAZOLE SOD DR 40 MG TAB 14 $313.52 $8.50 $305.02 97% WESTERN DRUG SPRINGERVILLE, AZ
FAMOTIDINE 20 MG TABLET 60 $167.85 $12.09 $155.76 93% SYMBRIA RX SERVICES WOODRIDGE, IL
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You can also view our Help & FAQ section for commonly asked questions or Call our Customer Care Support Team at: 1-833-300-0103