Burke's Main Street Pharmacy Prescription Savings Card

Tired of Paying Too Much for Prescriptions?

Get Your Free Burke's Main Street Pharmacy Card and Start Saving Today!

How It Works

Start Saving Today!

The Burke's Main Street Pharmacy pharmacy savings program gives millions of cardholders across the United States and Puerto Rico free access to discounts on prescription medications. Our program can be used by every member of the family including pets and can save you money even if you have prescription benefits.

How does Burke's Main Street Pharmacy do it? Our tremendous volume allows us to negotiate discounts with over 67,000 participating pharmacies nationwide and pass those savings directly on to you. Our online search tool allows you to compare prices at local pharmacies without leaving your home.

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Mission Statement

Our Mission is to Save You Money

Burke's Main Street Pharmacy is dedicated to helping improve the health and wellness of all individuals and their pets by giving them access to affordable prescription medications.

Find out more about us and the organizations we partner with.

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Program Highlights

Too Good NOT to be True

The Burke's Main Street Pharmacy medication savings program provides discounts of up to 87% off retail prices at all major chains and most independent pharmacies nationwide.

  • Absolutely FREE access to savings

    And you will always pay the lower of your insurance copay, the cash price or the Burke's Main Street Pharmacy discounted price.

  • Works on all FDA approved medications

    Including over-the-counter medications with a valid prescription.

  • Never Expires

    You can use the same card again and again at all participating pharmacies unlike single use coupons.

  • No enrollment or personal information required

    Burke's Main Street Pharmacy is always active with no registration to complete, and no setup or subscription fees.

  • Accepted at 67,000+ pharmacies nationwide

    Including all major retail pharmacies, big box stores, supermarkets and most independent pharmacies.

  • Works for Pet Medications

    If your pet has a prescription that has a human equivalent, our program can help.

  • Everyone is eligible

    No income or age restrictions.

  • Works for insured, uninsured and underinsured

    Everyone has the ability to save with our free card.

  • Multiple ways to get your free card

    Either print, text, email, download or request a physical card to be mailed. You can even share it on Facebook and Twitter.

What People Are Saying

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Recent Member Savings

This Could be You!

Use our online pricing tool to find local pharmacies with the lowest price for your medications.

Medication Count Retail Paid Savings Pharmacy Location
HYDROCODONE-ACETAMINOPHEN 10-3 90 $138.99 $17.57 $121.42 87% Winn Dixie PORT ST. JOHN, FL
ONDANSETRON HCL 8 MG TABLET 20 $779.67 $17.23 $762.44 98% BEN FRANKLIN APOTHECARY DUNCANVILLE, TX
CIPROFLOXACIN HCL 500 MG TAB 14 $75.15 $10.16 $64.99 86% CENTRX PHARMACY DESERT SPRINGS LAS VEGAS, NV
ONDANSETRON ODT 4 MG TABLET 20 $472.26 $28.59 $443.67 94% FRAZEYSBURG PHARMACY FRAZEYSBURG, OH
MORPHINE SULF ER 30 MG TABLET 90 $438.20 $123.84 $314.36 72% CONWAY'S EASTSIDE PHARMACY MT VERNON, OH
HYDROCODONE-ACETAMINOPHEN 10-3 40 $54.99 $21.39 $33.60 61% Rite Aid DOWNINGTOWN, PA
METHOCARBAMOL 750 MG TABLET 40 $36.72 $11.00 $25.72 70% METHODIST COMMUNITY PHARMACY DALLAS, TX
OXYCODONE HCL (IR) 20 MG TAB 18 $106.60 $18.11 $88.49 83% YORKTOWN PHARMACY ELKINS PARK, PA
QULIPTA 60 MG TABLET 30 $1,194.20 $1,031.99 $162.21 14% NORTH BRONX PHARMACY BRONX, NY
LISINOPRIL 20 MG TABLET 90 $131.61 $12.93 $118.68 90% CANAL PHARMACY SPENCERVILLE, OH
HYDROCODONE-ACETAMINOPHEN 5-32 60 $47.59 $18.48 $29.11 61% FAMILY FRESH MARKET PHARMACY NEW RICHMOND, WI
OXYCODONE-ACETAMINOPHEN 10-325 30 $151.61 $10.63 $140.98 93% COLORA PHARMACY COLORA, MD
OXYCODONE-ACETAMINOPHEN 5-325 60 $96.33 $19.04 $77.29 80% KHN PHARMACY - FORT HAMILTON HAMILTON, OH
DOXYCYCLINE MONO 100 MG CAP 120 $65.32 $18.89 $46.43 71% CONWAY'S EASTSIDE PHARMACY MT VERNON, OH
LORAZEPAM 1 MG TABLET 15 $19.69 $7.05 $12.64 64% KHN PHARMACY - FORT HAMILTON HAMILTON, OH
DILTIAZEM HCL POWDER 60 $60.70 $17.12 $43.58 72% YORKTOWN PHARMACY ELKINS PARK, PA
CEPHALEXIN 500 MG CAPSULE 28 $60.69 $9.72 $50.97 84% BROAD AND LEHIGH PHARMACY PHILADELPHIA, PA
AIRDUO DIGIHALER 232-14 MCG 1 $627.72 $494.10 $133.62 21% KHN PHARMACY BEAVERCREEK BEAVERCREEK, OH
FLUOXETINE HCL 10 MG CAPSULE 30 $61.99 $14.60 $47.39 76% Rite Aid BELLINGHAM, WA
DULOXETINE HCL DR 60 MG CAP 30 $225.99 $31.34 $194.65 86% Rite Aid HILLSBORO, NH
TOPIRAMATE 25 MG TABLET 180 $117.95 $23.40 $94.55 80% CONWAY'S EASTSIDE PHARMACY MT VERNON, OH
TADALAFIL 20 MG TABLET 30 $2,184.32 $28.60 $2,155.72 99% COLLABORATIVE PHARMACY SERVICE MIAMISBURG, OH
FAMOTIDINE 40 MG TABLET 90 $297.99 $33.22 $264.77 89% Rite Aid TUSTIN, CA
PREGABALIN 75 MG CAPSULE 12 $143.99 $17.69 $126.30 88% Rite Aid HARRISBURG, PA
AMOX-CLAV 875-125 MG TABLET 14 $75.73 $21.35 $54.38 72% SALUMED PHARMACY BRENTWOOD BRENTWOOD, NY
CLONAZEPAM 0.5 MG TABLET 60 $49.97 $8.55 $41.42 83% RAINBOW DISCOUNT DRUGS CITRUS SPRINGS, FL
QULIPTA 60 MG TABLET 30 $1,194.20 $1,031.99 $162.21 14% BROOK SPECIALTY PHARMACY BRONX, NY
TRAZODONE 100 MG TABLET 120 $130.99 $23.33 $107.66 82% Rite Aid SHELBY, OH
SIMVASTATIN 20 MG TABLET 90 $82.69 $10.26 $72.43 88% VONS PHARMACY LAKEWOOD, CA
TRAMADOL HCL 50 MG TABLET 120 $103.09 $13.58 $89.51 87% MT CRISTO PHARMACY LLC SUNLAND PARK, NM
AZITHROMYCIN 500 MG TABLET 7 $132.99 $28.80 $104.19 78% Rite Aid WEST HILLS, CA
QULIPTA 60 MG TABLET 30 $1,194.20 $1,031.99 $162.21 14% NORTH BRONX PHARMACY BRONX, NY
QUETIAPINE FUMARATE 100 MG TAB 28 $37.60 $8.64 $28.96 77% GUIDEPOINT PHARMACY ROCHESTER, MN
TIZANIDINE HCL 4 MG TABLET 60 $93.99 $9.25 $84.74 90% CREEKSIDE PHARMACY CORPORATION CUMMING, GA
AMLODIPINE BESYLATE 5 MG TAB 90 $139.99 $24.95 $115.04 82% Rite Aid MONROE, CT
VENLAFAXINE HCL ER 75 MG CAP 30 $140.00 $12.61 $127.39 91% PILL BOX PHARMACY ALBERTVILLE, AL
FREESTYLE LITE TEST STRIP 100 $185.99 $155.59 $30.40 16% CVS/pharmacy MATTAPAN, MA
SYNTHROID 100 MCG TABLET 30 $62.59 $51.55 $11.04 18% SOUTHSIDE FAMILY PHARMACY, INC SOUTHSIDE, AL
GLIMEPIRIDE 4 MG TABLET 60 $79.99 $24.12 $55.87 70% Rite Aid MERCED, CA
TRAMADOL HCL 50 MG TABLET 180 $198.59 $16.38 $182.21 92% SOUTHSIDE FAMILY PHARMACY, INC SOUTHSIDE, AL
OXYCODONE HCL (IR) 30 MG TAB 45 $223.73 $15.69 $208.04 93% BARON II DRUG & SURGICAL MOONACHIE, NJ
AMOX-CLAV 875-125 MG TABLET 10 $55.52 $18.11 $37.41 67% CITY DRUG STORE ALPINE, TX
BENZONATATE 100 MG CAPSULE 50 $365.42 $16.61 $348.81 95% WEBB'S SQUARE PHARMACY DAVENPORT, FL
VITAMIN D2 1.25 MG(50,000 UNIT 4 $24.89 $9.07 $15.82 64% SOUTH SAN MEDICAL BUILDING PHA SAN ANTONIO, TX
AMLODIPINE BESYLATE 5 MG TAB 90 $139.99 $24.95 $115.04 82% Rite Aid GOLETA, CA
TRAMADOL HCL 50 MG TABLET 112 $96.99 $20.57 $76.42 79% Rite Aid MILL CREEK, WA
PREGABALIN 25 MG CAPSULE 20 $172.55 $10.68 $161.87 94% CIRCLE S PHARMACY PAHOKEE, FL
LOSARTAN POTASSIUM 50 MG TAB 180 $490.72 $23.47 $467.25 95% PILL BOX PHARMACY FRANKLIN, WV
LEVETIRACETAM 500 MG TABLET 14 $59.20 $8.50 $50.70 86% KAWEAH DELTA PHARMACY VISALIA, CA
CLONAZEPAM 0.5 MG TABLET 60 $65.49 $8.55 $56.94 87% ICARERX PHARMACY - NEWPORT NEWPORT, AR
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You can also view our Help & FAQ section for commonly asked questions or Call our Customer Care Support Team at: 1-833-300-0103